InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Renbp

Summary

InnateDB Protein

IDBP-251882.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Renbp

Protein Name

renin binding protein

Synonyms

Age; Rnbp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110020

InnateDB Gene

IDBG-154507 (Renbp)

Protein Structure

UniProt Annotation

Function

Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. {ECO:0000269PubMed:22692205}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004857	enzyme inhibitor activity
GO:0005524	ATP binding
GO:0042803	protein homodimerization activity
GO:0050121	N-acylglucosamine 2-epimerase activity

Biological Process

GO:0006044	N-acetylglucosamine metabolic process
GO:0006051	N-acetylmannosamine metabolic process
GO:0010951	negative regulation of endopeptidase activity
GO:0019262	N-acetylneuraminate catabolic process