Version 5.4
Mus musculus Gene: Renbp
Summary
InnateDB Gene IDBG-154507.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Renbp
Gene Name renin binding protein
Synonyms Age; Rnbp
Species Mus musculus
Ensembl Gene ENSMUSG00000031387
Encoded Proteins
IDBP-251882
renin binding protein
IDBP-273774
renin binding protein
IDBP-534719
renin binding protein
IDBP-625904
renin binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102032:
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:73922121-73930850
Strand Reverse strand
Band A7.3
Transcripts
ENSMUST00000114379 ENSMUSP00000110020
ENSMUST00000116578 ENSMUSP00000112277
ENSMUST00000135213
ENSMUST00000135711
ENSMUST00000155597 ENSMUSP00000116549
ENSMUST00000144771
ENSMUST00000149130
ENSMUST00000146371
ENSMUST00000150241
ENSMUST00000165359 ENSMUSP00000132729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004857 enzyme inhibitor activity
GO:0005524 ATP binding
GO:0017076 purine nucleotide binding
GO:0042803 protein homodimerization activity
GO:0050121 N-acylglucosamine 2-epimerase activity
Biological Process
GO:0006044 N-acetylglucosamine metabolic process
GO:0006051 N-acetylmannosamine metabolic process
GO:0010951 negative regulation of endopeptidase activity
GO:0019262 N-acetylneuraminate catabolic process
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102032
View Gene Order
ENSBTAG00000047827
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
INOH website
Aminosugars metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.236969
RefSeq NM_001164704 NM_023132 XM_006527916
OMIM
CCDS CCDS41015 CCDS57763
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca