InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prkx

Summary

InnateDB Protein

IDBP-252588.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Prkx

Protein Name

protein kinase, X-linked

Synonyms

Pkare; PKX1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109678

InnateDB Gene

IDBG-157778 (Prkx)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004691	cAMP-dependent protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0001525	angiogenesis
GO:0001935	endothelial cell proliferation
GO:0006468	protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0030099	myeloid cell differentiation
GO:0030155	regulation of cell adhesion
GO:0030334	regulation of cell migration
GO:0031589	cell-substrate adhesion
GO:0043542	endothelial cell migration
GO:0046777	protein autophosphorylation
GO:0060562	epithelial tube morphogenesis
GO:0060993	kidney morphogenesis
GO:2000696	regulation of epithelial cell differentiation involved in kidney development

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1309999

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt