Version 5.4
Mus musculus Protein: Aph1b
Summary
InnateDB Protein IDBP-253276.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aph1b
Protein Name anterior pharynx defective 1b homolog (C. elegans)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000109359
InnateDB Gene IDBG-179986 (Aph1b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0016485 protein processing
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3522097
InterPro IPR009294 Gamma-secretase subunit Aph-1
PFAM PF06105
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8WHK7
UniProt Splice Variant
Entrez Gene 208117
UniGene Mm.473445
RefSeq
MGI ID
MGI Symbol Aph1b
OMIM
CCDS
HPRD
IMGT
EMBL AC134429 AC142504
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca