Version 5.4
Mus musculus Protein: Prickle2
Summary
InnateDB Protein IDBP-253863.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prickle2
Protein Name prickle homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000109073
InnateDB Gene IDBG-171127 (Prickle2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus membrane {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the hippocampus and cerebral cortex. {ECO:0000269PubMed:21276947}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0031175 neuron projection development
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
Cellular Component
GO:0005737 cytoplasm
GO:0016327 apicolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1925144
InterPro IPR001781 Zinc finger, LIM-type
IPR010442 PET domain
PFAM PF00412
PF06297
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80Y24
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 243548
UniGene Mm.405243
RefSeq NP_001127931
MGI ID
MGI Symbol Prickle2
OMIM
CCDS CCDS51854
HPRD
IMGT
EMBL BC050793 BC145754 CH466523
GenPept AAH50793 AAI45755 EDK99322

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca