InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Foxp4

Summary

InnateDB Protein

IDBP-254237.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Foxp4

Protein Name

forkhead box P4

Synonyms

1200010K03Rik; 2310007G05Rik; mFKHLA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108888

InnateDB Gene

IDBG-189596 (Foxp4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0007507	heart development
GO:0048617	embryonic foregut morphogenesis
GO:0061140	lung secretory cell differentiation
GO:1901249	regulation of lung goblet cell differentiation
GO:1901250	negative regulation of lung goblet cell differentiation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1921373

InterPro

IPR001766 Transcription factor, fork head

PFAM

PF00250

PRINTS

PR00053

PIRSF

SMART

SM00339

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z726

UniProt Splice Variant

Entrez Gene

74123

UniGene

RefSeq

MGI ID

MGI Symbol

Foxp4

OMIM

CCDS

HPRD

IMGT

EMBL

AC113536 AC164306

GenPept