Mus musculus Protein: Trmt2b
Summary
InnateDB Protein IDBP-254267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt2b
Protein Name TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000108878
InnateDB Gene IDBG-170850 (Trmt2b)
Protein Structure
UniProt Annotation
Function Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0032259 methylation
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:2442530
InterPro IPR007848 Methyltransferase small domain
IPR010280 (Uracil-5)-methyltransferase family
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF05175
PF05958
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BQJ6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 215201
UniGene Mm.289368
RefSeq NP_001161466
MGI ID
MGI Symbol Trmt2b
OMIM
CCDS CCDS41121
HPRD
IMGT
EMBL AK028999 AK049523 AL672215 BC056937
GenPept AAH56937 BAC26233 BAC33793 CAM15919