Version 5.4
Mus musculus Gene: Trmt2b
Summary
InnateDB Gene IDBG-170850.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt2b
Gene Name TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000067369
Encoded Proteins
IDBP-170852
TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
IDBP-170854
TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
IDBP-254267
TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
IDBP-789809
TRM2 tRNA methyltransferase 2B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188917:
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:134222339-134276984
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000087541 ENSMUSP00000084820
ENSMUST00000087540 ENSMUSP00000084819
ENSMUST00000113252 ENSMUSP00000108878
ENSMUST00000128115 ENSMUSP00000138612
ENSMUST00000145066
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0032259 methylation
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000188917
View Gene Order
Cross-References
SwissProt Q8BQJ6
TrEMBL Q8C8J3 S4R2E5
UniProt Splice Variant
Entrez Gene 215201
UniGene Mm.289368
RefSeq NM_001167994 NM_001167995 NM_172540
OMIM
CCDS CCDS41121 CCDS53183
HPRD
IMGT
MGI ID MGI:2442530
MGI Symbol Trmt2b
EMBL AK028999 AK046928 AK049523 AL672215 BC056937
GenPept AAH56937 BAC26233 BAC32921 BAC33793 CAM15919
RNA Seq Atlas 215201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca