Version 5.4
Mus musculus Protein: Trnt1
Summary
InnateDB Protein IDBP-254282.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trnt1
Protein Name tRNA nucleotidyl transferase, CCA-adding, 1
Synonyms 2410043H24Rik; 2610044E04Rik; 9830143O18Rik; AA408384; C76540; CGI-47; mt-Trat;
Species Mus musculus
Ensembl Protein ENSMUSP00000108873
InnateDB Gene IDBG-173949 (Trnt1)
Protein Structure
UniProt Annotation
Function Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004810 tRNA adenylyltransferase activity
GO:0005524 ATP binding
GO:0009022 tRNA nucleotidyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0052927 CTP:tRNA cytidylyltransferase activity
GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity
GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0042780 tRNA 3'-end processing
Cellular Component
GO:0005739 mitochondrion
GO:0005813 centrosome
Protein Structure and Domains
PDB ID MGI:1917297
InterPro IPR002646 Poly A polymerase, head domain
PFAM PF01743
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K1J6
PhosphoSite PhosphoSite-Q8K1J6
TrEMBL
UniProt Splice Variant
Entrez Gene 70047
UniGene Mm.487966
RefSeq NP_001229289
MGI ID
MGI Symbol Trnt1
OMIM
CCDS CCDS57443
HPRD
IMGT
EMBL AB063106 AK011764 AK135791 AK152739 AK166804 BC031764
GenPept AAH31764 BAB27827 BAB70663 BAE22664 BAE31459 BAE39032

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca