Version 5.4
Mus musculus Gene: Trnt1
Summary
InnateDB Gene IDBG-173949.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trnt1
Gene Name tRNA nucleotidyl transferase, CCA-adding, 1
Synonyms 2410043H24Rik; 2610044E04Rik; 9830143O18Rik; AA408384; C76540; CGI-47; mt-Trat
Species Mus musculus
Ensembl Gene ENSMUSG00000013736
Encoded Proteins
IDBP-173951
tRNA nucleotidyl transferase, CCA-adding, 1
IDBP-254278
tRNA nucleotidyl transferase, CCA-adding, 1
IDBP-254280
tRNA nucleotidyl transferase, CCA-adding, 1
IDBP-254282
tRNA nucleotidyl transferase, CCA-adding, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072756:
The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:106769120-106782474
Strand Forward strand
Band E1
Transcripts
ENSMUST00000057578 ENSMUSP00000060900
ENSMUST00000113249 ENSMUSP00000108875
ENSMUST00000113248 ENSMUSP00000108874
ENSMUST00000113247 ENSMUSP00000108873
ENSMUST00000147084
ENSMUST00000154026
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004810 tRNA adenylyltransferase activity
GO:0005524 ATP binding
GO:0009022 tRNA nucleotidyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0052927 CTP:tRNA cytidylyltransferase activity
GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity
GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity
Biological Process
GO:0001680 tRNA 3'-terminal CCA addition
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0042780 tRNA 3'-end processing
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072756
View Gene Order
ENSBTAG00000019534
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.196332 Mm.448475 Mm.487966
RefSeq NM_001242358 NM_001242360 NM_027296 XM_006506581
OMIM
CCDS CCDS20397 CCDS57443
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca