InnateDB Protein
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IDBP-254578.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tada3
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Protein Name
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transcriptional adaptor 3
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Synonyms
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1110004B19Rik; ADA3; AI987856; Tada3l;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000108736
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InnateDB Gene
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IDBG-176433 (Tada3)
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Protein Structure
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Function |
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation (By similarity). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
|
Protein-Protein |
12
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
44 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004402
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histone acetyltransferase activity
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GO:0005515
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protein binding
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GO:0016922
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ligand-dependent nuclear receptor binding
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GO:0019904
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protein domain specific binding
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GO:0030374
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ligand-dependent nuclear receptor transcription coactivator activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1915724
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InterPro |
IPR019340
Histone acetyltransferases subunit 3
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PFAM |
PF10198
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8R0L9
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PhosphoSite |
PhosphoSite-Q8R0L9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
101206
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UniGene |
Mm.266811
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RefSeq |
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MGI ID |
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MGI Symbol |
Tada3
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AF383154
AK003405
AK078906
BC022707
BC023879
BC026630
BC032195
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GenPept |
AAH22707
AAH23879
AAH26630
AAH32195
AAM21463
BAB22769
BAC37451
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