InnateDB Protein
|
IDBP-255172.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Arhgap15
|
Protein Name
|
Rho GTPase activating protein 15
|
Synonyms
|
5830480G12Rik;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000108441
|
InnateDB Gene
|
IDBG-168042 (Arhgap15)
|
Protein Structure
|
|
Function |
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
5 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0030675
|
Rac GTPase activator activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1923367
|
InterPro |
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q811M1
|
PhosphoSite |
PhosphoSite-Q811M1
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
76117
|
UniGene |
Mm.415835
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Arhgap15
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AK031022
AK170537
AK172407
AL732320
AL844535
AL845160
AL928611
AL935152
BC024887
BC034881
|
GenPept |
AAH24887
AAH34881
BAC27217
BAE41865
BAE42992
CAM15030
CAM17611
CAM19036
CAM20252
CAM27855
|
|
|