Mus musculus Protein: Fgd1
Summary
InnateDB Protein IDBP-255488.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Fgd1
Protein Name FYVE, RhoGEF and PH domain containing 1
Synonyms ZFYVE3;
Species Mus musculus
Ensembl Protein ENSMUSP00000108305
InnateDB Gene IDBG-178715 (Fgd1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0031267 small GTPase binding
GO:0046872 metal ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0030036 actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0043088 regulation of Cdc42 GTPase activity
GO:0046847 filopodium assembly
Cellular Component
GO:0001726 ruffle
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0030027 lamellipodium
Protein Structure and Domains
PDB ID MGI:104566
InterPro IPR000219 Dbl homology (DH) domain
IPR000306 FYVE zinc finger
IPR001849 Pleckstrin homology domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
PFAM PF00621
PF01363
PF00169
PRINTS
PIRSF
SMART SM00325
SM00064
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q99K79
UniProt Splice Variant
Entrez Gene 14163
UniGene Mm.8142
RefSeq XP_006528762
MGI ID
MGI Symbol Fgd1
OMIM
CCDS
HPRD
IMGT
EMBL AL805937 BC004838
GenPept AAH04838