InnateDB Protein
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IDBP-255724.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Klf8
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Protein Name
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Kruppel-like factor 8
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000108193
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InnateDB Gene
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IDBG-180756 (Klf8)
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Protein Structure
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Function |
Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK) (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
8 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2442430
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InterPro |
IPR007087
Zinc finger, C2H2
IPR015880
Zinc finger, C2H2-like
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PFAM |
PF00096
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PRINTS |
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PIRSF |
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SMART |
SM00355
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BLM0
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PhosphoSite |
PhosphoSite-Q8BLM0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
245671
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UniGene |
Mm.489131
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RefSeq |
NP_776141
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MGI ID |
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MGI Symbol |
Klf8
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OMIM |
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CCDS |
CCDS30481
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HPRD |
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IMGT |
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EMBL |
AK044185
BC070442
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GenPept |
AAH70442
BAC31807
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