InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bmx

Summary

InnateDB Protein

IDBP-256369.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bmx

Protein Name

BMX non-receptor tyrosine kinase

Synonyms

Etk; Etk/Bmx; Tyro8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107884

InnateDB Gene

IDBG-184635 (Bmx)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0004715	non-membrane spanning protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0046872	metal ion binding

Biological Process

GO:0006468	protein phosphorylation
GO:0006915	apoptotic process
GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0035556	intracellular signal transduction
GO:0046777	protein autophosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0032587	ruffle membrane

Protein Structure and Domains

PDB ID

MGI:1101778

InterPro

IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001562 Zinc finger, Btk motif
IPR001849 Pleckstrin homology domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF00017
PF14633
PF07714
PF00779
PF00169

PRINTS

PR00401
PR00109
PR00402

PIRSF

SMART

SM00252
SM00107
SM00233
SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt