InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hoxd3

Summary

InnateDB Protein

IDBP-256980.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hoxd3

Protein Name

homeobox D3

Synonyms

Hox-4.1; Hox-5.5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107614

InnateDB Gene

IDBG-256978 (Hoxd3)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Detected in adult kidney, but not in other adult tissues tested. {ECO:0000269PubMed:8710855}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007160	cell-matrix adhesion
GO:0007219	Notch signaling pathway
GO:0007275	multicellular organismal development
GO:0010628	positive regulation of gene expression