InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cfh

Summary

InnateDB Protein

IDBP-256988.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cfh

Protein Name

complement component factor h

Synonyms

Mud-1; NOM; Sas-1; Sas1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107607

InnateDB Gene

IDBG-196803 (Cfh)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001851	complement component C3b binding
GO:0008201	heparin binding

Biological Process

GO:0006957	complement activation, alternative pathway
GO:0030449	regulation of complement activation
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

MGI:88385

InterPro

IPR000436 Sushi/SCR/CCP

PFAM

PF00084

PRINTS

PIRSF

SMART

SM00032

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8C5S1

UniProt Splice Variant

Entrez Gene

12628

UniGene

Mm.8655

RefSeq

NP_034018

MGI ID

2YBY

MGI Symbol

Cfh

OMIM

CCDS

CCDS48388

HPRD

IMGT

EMBL

AC161408 AH001909 AK077187 BC066092 J02891 M12660

GenPept

AAA37759 AAA37762 AAA37795 AAH66092 BAC36669