InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rgs13

Summary

InnateDB Protein

IDBP-257061.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rgs13

Protein Name

regulator of G-protein signaling 13

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107572

InnateDB Gene

IDBG-197148 (Rgs13)

Protein Structure

UniProt Annotation

Function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)- alpha.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005096	GTPase activator activity
GO:0005515	protein binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0043547	positive regulation of GTPase activity
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway