Version 5.4
Mus musculus Protein: Pla2g4a
Summary
InnateDB Protein IDBP-257083.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Pla2g4a
Protein Name phospholipase A2, group IVA (cytosolic, calcium-dependent)
Synonyms cPLA2; cPLA2alpha; Pla2g4;
Species Mus musculus
Ensembl Protein ENSMUSP00000107557
InnateDB Gene IDBG-197265 (Pla2g4a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004620 phospholipase activity
GO:0005515 protein binding
Biological Process
GO:0008152 metabolic process
GO:0009395 phospholipid catabolic process
GO:0042127 regulation of cell proliferation
GO:0045087 innate immune response (InnateDB)
GO:0046456 icosanoid biosynthetic process
GO:0050482 arachidonic acid secretion
GO:0071236 cellular response to antibiotic
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1195256
InterPro IPR000008 C2 domain
IPR002642 Lysophospholipase, catalytic domain
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase
PFAM PF00168
PF01735
PRINTS PR00360
PIRSF
SMART SM00239
SM00022
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9DBX5
UniProt Splice Variant
Entrez Gene 18783
UniGene Mm.4186
RefSeq XP_006529315
MGI ID
MGI Symbol Pla2g4a
OMIM
CCDS
HPRD
IMGT
EMBL AC120138 AC158151 AK004701
GenPept BAB23486

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca