InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dclk3

Summary

InnateDB Protein

IDBP-257193.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dclk3

Protein Name

doublecortin-like kinase 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107510

InnateDB Gene

IDBG-202865 (Dclk3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:16684769}. Nucleus {ECO:0000269PubMed:16684769}.

Disease Associations

Tissue Specificity

Highly expressed in brain and to a lower extent in liver and kidney. {ECO:0000269PubMed:16684769}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:3039580

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR003533 Doublecortin domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF03607

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00537
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt