InnateDB Protein
|
IDBP-25762.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
GTPBP10
|
Protein Name
|
GTP-binding protein 10 (putative)
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000369398
|
InnateDB Gene
|
IDBG-25756 (GTPBP10)
|
Protein Structure
|
|
Function |
May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed. {ECO:0000269PubMed:17054726}.
|
Subcellular Localization |
Nucleus, nucleolus {ECO:0000269PubMed:17054726}. Chromosome {ECO:0000269PubMed:17054726}. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase. Gradually re-assembles into the nucleolus at late anaphase to telophase.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR006169
GTP1/OBG domain
|
PFAM |
PF01018
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
A4D1E9
|
PhosphoSite |
PhosphoSite-A4D1E9
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
85865
|
UniGene |
Hs.734999
|
RefSeq |
|
HUGO |
HGNC:25106
|
OMIM |
610920
|
CCDS |
|
HPRD |
14262
|
IMGT |
|
EMBL |
AC002064
AC006153
AF351613
AK095561
AK294325
BC004923
BC021573
BC107714
CH236949
CH471091
CR933597
|
GenPept |
AAD15550
AAH04923
AAH21573
AAI07715
AAN76513
BAC04573
BAG57597
CAI45922
EAL24164
EAW76880
EAW76882
|
|
|