InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pou2f1

Summary

InnateDB Protein

IDBP-258133.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pou2f1

Protein Name

POU domain, class 2, transcription factor 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107056

InnateDB Gene

IDBG-202815 (Pou2f1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	13 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	52 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030910	olfactory placode formation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060235	lens induction in camera-type eye

Cellular Component

GO:0005634	nucleus
GO:0005667	transcription factor complex

Protein Structure and Domains

PDB ID

InterPro

IPR000327 POU-specific
IPR000972 Octamer-binding transcription factor
IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR010982 Lambda repressor-like, DNA-binding domain
IPR013847 POU domain

PFAM

PF00157
PF00046
PF13413

PRINTS

PR00029
PR00028

PIRSF

SMART

SM00352
SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt