Version 5.4
Mus musculus Protein: Slc1a2
Summary
InnateDB Protein IDBP-258602.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Slc1a2
Protein Name solute carrier family 1 (glial high affinity glutamate transporter), member 2
Synonyms 1700091C19Rik; 2900019G14Rik; AI159670; Eaat2; GLT-1; GLT1; MGLT1;
Species Mus musculus
Ensembl Protein ENSMUSP00000106844
InnateDB Gene IDBG-193462 (Slc1a2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005313 L-glutamate transmembrane transporter activity
GO:0015501 glutamate:sodium symporter activity
GO:0017153 sodium:dicarboxylate symporter activity
Biological Process
GO:0006835 dicarboxylic acid transport
GO:0007399 nervous system development
GO:0007632 visual behavior
GO:0009416 response to light stimulus
GO:0009611 response to wounding
GO:0010259 multicellular organismal aging
GO:0015813 L-glutamate transport
GO:0021537 telencephalon development
GO:0030534 adult behavior
GO:0031668 cellular response to extracellular stimulus
GO:0035264 multicellular organism growth
GO:0042493 response to drug
GO:0043200 response to amino acid
GO:0046326 positive regulation of glucose import
GO:0051938 L-glutamate import
GO:0070779 D-aspartate import
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0030424 axon
GO:0030673 axolemma
Protein Structure and Domains
PDB ID MGI:101931
InterPro IPR001991 Sodium:dicarboxylate symporter
PFAM PF00375
PRINTS PR00173
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2AQI7
UniProt Splice Variant
Entrez Gene 20511
UniGene Mm.479346
RefSeq XP_006499110
MGI ID
MGI Symbol Slc1a2
OMIM
CCDS
HPRD
IMGT
EMBL AL844155 AL844605
GenPept CAM27622 CAM27626

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca