InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdc42bpa

Summary

InnateDB Protein

IDBP-258803.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Cdc42bpa

Protein Name

CDC42 binding protein kinase alpha

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106746

InnateDB Gene

IDBG-207029 (Cdc42bpa)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005083	small GTPase regulator activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042802	identical protein binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0006468	protein phosphorylation
GO:0007097	nuclear migration
GO:0016477	cell migration
GO:0031032	actomyosin structure organization
GO:0031532	actin cytoskeleton reorganization
GO:0035556	intracellular signal transduction
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0042641	actomyosin
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2441841

InterPro

IPR000095 CRIB domain
IPR000719 Protein kinase domain
IPR000961 AGC-kinase, C-terminal
IPR001180 Citron-like
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001849 Pleckstrin homology domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR014930 Myotonic dystrophy protein kinase, coiled coil
IPR017892 Protein kinase, C-terminal
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM