Version 5.4
| Mus musculus Protein: Adam28 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-258886.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adam28 | ||||||||
| Protein Name | a disintegrin and metallopeptidase domain 28 | ||||||||
| Synonyms | C130072N01Rik; D430033C21Rik; Dtgn1; eMDCII; MDC-L; MDC-Lm; MDC-Ls; MDCL; TECADAM; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000106701 | ||||||||
| InnateDB Gene | IDBG-176814 (Adam28) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | ||||||||
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Strong expression in thymic epithelial cells and developmentally related tissues including the trachea, thyroid, lung and stomach, but not in lymphocytes. Expressed at high levels also in epididymis. In contrast with human is not expressed in immature or mature lymphocyte populations of thymocytes, lymph node, spleen, and bone marrow. {ECO:0000269PubMed:11867223}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:105988 | ||||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001590 Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF00008
PF01421 PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||
| SMART |
SM00181
SM00050 SM00608 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9JLN6 | ||||||||
| PhosphoSite | PhosphoSite-Q9JLN6 | ||||||||
| TrEMBL | Q60619 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 13522 | ||||||||
| UniGene | |||||||||
| RefSeq | NP_001041640 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Adam28 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36964 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF153350 AF163290 AF163291 AF163292 BC058782 U06146 | ||||||||
| GenPept | AAA18425 AAF71993 AAH58782 AAM21935 AAM21936 AAM21937 | ||||||||