Mus musculus Gene: Adam28
Summary
InnateDB Gene IDBG-176814.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adam28
Gene Name a disintegrin and metallopeptidase domain 28
Synonyms C130072N01Rik; D430033C21Rik; Dtgn1; eMDCII; MDC-L; MDC-Lm; MDC-Ls; MDCL; TECADAM
Species Mus musculus
Ensembl Gene ENSMUSG00000014725
Encoded Proteins
a disintegrin and metallopeptidase domain 28
a disintegrin and metallopeptidase domain 28
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000042980:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:68606027-68655842
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000022642 ENSMUSP00000022642
ENSMUST00000111072 ENSMUSP00000106701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Alpha4 beta1 integrin signaling events
Cross-References
SwissProt Q9JLN6
TrEMBL Q60619
UniProt Splice Variant
Entrez Gene 13522
UniGene
RefSeq NM_010082 NM_183366 XM_006518514 NM_001048175
OMIM
CCDS CCDS36965 CCDS36964
HPRD
IMGT
MGI ID MGI:105988
MGI Symbol Adam28
EMBL AF153350 AF163290 AF163291 AF163292 BC058782 U06146
GenPept AAA18425 AAF71993 AAH58782 AAM21935 AAM21936 AAM21937
RNA Seq Atlas 13522