Mus musculus Protein: Lpin1
Summary
InnateDB Protein IDBP-258899.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lpin1
Protein Name lipin 1
Synonyms 4631420P06; fld; Kiaa0188; Lipin1; mKIAA0188;
Species Mus musculus
Ensembl Protein ENSMUSP00000106696
InnateDB Gene IDBG-129213 (Lpin1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001085 RNA polymerase II transcription factor binding
GO:0005515 protein binding
GO:0008195 phosphatidate phosphatase activity
GO:0042826 histone deacetylase binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006629 lipid metabolic process
GO:0009062 fatty acid catabolic process
GO:0016311 dephosphorylation
GO:0019432 triglyceride biosynthetic process
GO:0031065 positive regulation of histone deacetylation
GO:0031529 ruffle organization
GO:0031532 actin cytoskeleton reorganization
GO:0032869 cellular response to insulin stimulus
GO:0045598 regulation of fat cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:1891340
InterPro IPR007651 Lipin, N-terminal
IPR013209 LNS2, Lipin/Ned1/Smp2
IPR017986 WD40-repeat-containing domain
IPR023214 HAD-like domain
PFAM PF04571
PF08235
PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART SM00775
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9QKQ5
UniProt Splice Variant
Entrez Gene 14245
UniGene Mm.470809
RefSeq NP_766538
MGI ID
MGI Symbol Lpin1
OMIM
CCDS CCDS25823
HPRD
IMGT
EMBL AC159631
GenPept