Mus musculus Protein: Cyth3
Summary
InnateDB Protein IDBP-259649.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Cyth3
Protein Name cytohesin 3
Synonyms AI648983; ARNO3; CLM3; Grp1; Pscd3;
Species Mus musculus
Ensembl Protein ENSMUSP00000106355
InnateDB Gene IDBG-207822 (Cyth3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
Biological Process
GO:0032012 regulation of ARF protein signal transduction
GO:0043087 regulation of GTPase activity
GO:0045785 positive regulation of cell adhesion
GO:0048193 Golgi vesicle transport
GO:0090162 establishment of epithelial cell polarity
Cellular Component
GO:0001726 ruffle
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
Protein Structure and Domains
PDB ID MGI:1335107
InterPro IPR000904 Sec7 domain
IPR001849 Pleckstrin homology domain
PFAM PF01369
PF00169
PRINTS
PIRSF
SMART SM00222
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E8Q4
UniProt Splice Variant
Entrez Gene 19159
UniGene Mm.398925
RefSeq NP_001157020
MGI ID
MGI Symbol Cyth3
OMIM
CCDS CCDS51691
HPRD
IMGT
EMBL AC136746 AC163995 CH466529
GenPept EDL19039