InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arhgap5

Summary

InnateDB Protein

IDBP-259662.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Arhgap5

Protein Name

Rho GTPase activating protein 5

Synonyms

p190-B; p190B;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106353

InnateDB Gene

IDBG-139100 (Arhgap5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0042169	SH2 domain binding

Biological Process

GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0008361	regulation of cell size
GO:0030335	positive regulation of cell migration
GO:0030879	mammary gland development

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

MGI:1332637

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR001806 Small GTPase superfamily
IPR002713 FF domain
IPR008936 Rho GTPase activation protein
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00620
PF00071
PF01846

PRINTS

PR00449

PIRSF

SMART

SM00324
SM00441

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt