Version 5.4
Mus musculus Protein: Cops2
Summary
InnateDB Protein IDBP-260215.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Cops2
Protein Name COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
Synonyms AI315723; C85265; Csn2; Sgn2; TRIP-15; Trip15;
Species Mus musculus
Ensembl Protein ENSMUSP00000106089
InnateDB Gene IDBG-203870 (Cops2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 86 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 86 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
Biological Process
GO:0008283 cell proliferation
GO:0035914 skeletal muscle cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0008180 COP9 signalosome
Protein Structure and Domains
PDB ID MGI:1330276
InterPro IPR000717 Proteasome component (PCI) domain
IPR013143 PCI/PINT associated module
PFAM PF01399
PRINTS
PIRSF
SMART SM00088
SM00753
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2AQE4
UniProt Splice Variant
Entrez Gene 12848
UniGene Mm.470135
RefSeq
MGI ID
MGI Symbol Cops2
OMIM
CCDS
HPRD
IMGT
EMBL AL844580
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca