Version 5.4
Mus musculus Gene: Cops2
Summary
InnateDB Gene IDBG-203870.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cops2
Gene Name COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
Synonyms AI315723; C85265; Csn2; Sgn2; TRIP-15; Trip15
Species Mus musculus
Ensembl Gene ENSMUSG00000027206
Encoded Proteins
IDBP-203872
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
IDBP-260213
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
IDBP-260215
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166200:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125830304-125859139
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000028635 ENSMUSP00000028635
ENSMUST00000110463 ENSMUSP00000106090
ENSMUST00000110462 ENSMUSP00000106089
ENSMUST00000139343
ENSMUST00000152683
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 86 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 86 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0008283 cell proliferation
GO:0010388 cullin deneddylation
GO:0030182 neuron differentiation
GO:0035914 skeletal muscle cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008180 COP9 signalosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166200
View Gene Order
ENSBTAG00000013425
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.3596 Mm.394881 Mm.470135
RefSeq NM_001285507 NM_001285513 NM_009939
OMIM
CCDS CCDS16679 CCDS71133
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca