Homo sapiens Protein: CD2BP2
Summary
InnateDB Protein IDBP-26037.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD2BP2
Protein Name CD2 (cytoplasmic tail) binding protein 2
Synonyms FWP010; LIN1; PPP1R59; Snu40; U5-52K;
Species Homo sapiens
Ensembl Protein ENSP00000304903
InnateDB Gene IDBG-26035 (CD2BP2)
Protein Structure
UniProt Annotation
Function Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly. {ECO:0000269PubMed:15840814}.
Subcellular Localization Cytoplasm. Nucleus. Note=Predominantly nuclear.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 80 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 80 [view]
Protein-Protein 80 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005682 U5 snRNP
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID
InterPro IPR003169 GYF
PFAM PF02213
PRINTS
PIRSF
SMART SM00444
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95400
PhosphoSite PhosphoSite-O95400
TrEMBL Q5QTR6
UniProt Splice Variant
Entrez Gene 10421
UniGene Hs.737990
RefSeq NP_006101
HUGO HGNC:1656
OMIM 604470
CCDS CCDS10675
HPRD 05127
IMGT
EMBL AB033004 AF104222 AF109192 AK315708 BC000495 BC001947 CH471192
GenPept AAC84141 AAH00495 AAH01947 AAQ13502 BAA86492 BAG38069 EAW52260 EAW52261