InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Smoc1

Summary

InnateDB Protein

IDBP-260471.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Smoc1

Protein Name

SPARC related modular calcium binding 1

Synonyms

2600002F22Rik; AI848508; SRG;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105976

InnateDB Gene

IDBG-154151 (Smoc1)

Protein Structure

UniProt Annotation

Function

Probable regulator of osteoblast differentiation. Plays essential roles in both eye and limb development. {ECO:0000269PubMed:21194678, ECO:0000269PubMed:21750680}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. Note=In or around the basement membrane. {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed in many tissues with a strongest signal in ovary.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0050840	extracellular matrix binding

Biological Process

GO:0001654	eye development
GO:0007165	signal transduction
GO:0010811	positive regulation of cell-substrate adhesion
GO:0030154	cell differentiation
GO:0030198	extracellular matrix organization
GO:0045667	regulation of osteoblast differentiation
GO:0060173	limb development