Version 5.4
Mus musculus Protein: Fbxo8
Summary
InnateDB Protein IDBP-260519.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Fbxo8
Protein Name F-box protein 8
Synonyms Fbx8;
Species Mus musculus
Ensembl Protein ENSMUSP00000105951
InnateDB Gene IDBG-156105 (Fbxo8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0030036 actin cytoskeleton organization
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0030054 cell junction
Protein Structure and Domains
PDB ID MGI:1354696
InterPro IPR001810 F-box domain
PFAM PF00646
PF12937
PF13013
PRINTS
PIRSF
SMART SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q921R9
UniProt Splice Variant
Entrez Gene 50753
UniGene Mm.398860
RefSeq
MGI ID
MGI Symbol Fbxo8
OMIM
CCDS
HPRD
IMGT
EMBL AC116121 BC011100 CH466569
GenPept AAH11100 EDL28607

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca