InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpcpd1

Summary

InnateDB Protein

IDBP-260869.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpcpd1

Protein Name

glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)

Synonyms

2310004G06Rik; 2310032D16Rik; AU015213; Gde5; mKIAA1434; Prei4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000105769

InnateDB Gene

IDBG-207387 (Gpcpd1)

Protein Structure

UniProt Annotation

Function

May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. {ECO:0000269PubMed:20576599}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000269PubMed:20576599}.

Disease Associations

Tissue Specificity

Widely expressed with highest levels in skeletal muscle and heart. {ECO:0000269PubMed:20576599}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008081	phosphoric diester hydrolase activity
GO:0008889	glycerophosphodiester phosphodiesterase activity
GO:0030246	carbohydrate binding
GO:0047389	glycerophosphocholine phosphodiesterase activity
GO:2001070	starch binding

Biological Process

GO:0006071	glycerol metabolic process
GO:0006629	lipid metabolic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

MGI:104898

InterPro

IPR002044 Carbohydrate binding module family 20
IPR004129 Glycerophosphoryl diester phosphodiesterase
IPR013784 Carbohydrate-binding-like fold
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain

PFAM

PF00686

PRINTS

PIRSF

SMART

SM01065

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C0L9