Version 5.4
Mus musculus Protein: Tasp1
Summary
InnateDB Protein IDBP-261029.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tasp1
Protein Name taspase, threonine aspartase 1
Synonyms 4930485D02Rik; AW986064;
Species Mus musculus
Ensembl Protein ENSMUSP00000105706
InnateDB Gene IDBG-208035 (Tasp1)
Protein Structure
UniProt Annotation
Function Protease involved in KMT2A/MLL1 processing and, consequently, in the correct expression of the early HOXA gene cluster. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004298 threonine-type endopeptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
Protein Structure and Domains
PDB ID MGI:1923062
InterPro IPR000246 Peptidase T2, asparaginase 2
IPR029055 Nucleophile aminohydrolases, N-terminal
PFAM PF01112
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1G1
PhosphoSite PhosphoSite-Q8R1G1
TrEMBL
UniProt Splice Variant
Entrez Gene 75812
UniGene Mm.471012
RefSeq NP_001276540
MGI ID
MGI Symbol Tasp1
OMIM
CCDS CCDS16802
HPRD
IMGT
EMBL AK036512 AK050603 BC005776 BC024597
GenPept AAH05776 AAH24597 BAC29457 BAC34335

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca