Mus musculus Gene: Tasp1
Summary
InnateDB Gene IDBG-208035.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tasp1
Gene Name taspase, threonine aspartase 1
Synonyms 4930485D02Rik; AW986064
Species Mus musculus
Ensembl Gene ENSMUSG00000039033
Encoded Proteins
taspase, threonine aspartase 1
taspase, threonine aspartase 1
taspase, threonine aspartase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089123:
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:139833480-140066805
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000046656 ENSMUSP00000039546
ENSMUST00000099304 ENSMUSP00000096907
ENSMUST00000110079 ENSMUSP00000105706
ENSMUST00000124949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004298 threonine-type endopeptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q8R1G1
TrEMBL Q3UJT0
UniProt Splice Variant
Entrez Gene 75812
UniGene Mm.293449 Mm.471012
RefSeq NM_001159640 NM_001159641 NM_175225
OMIM
CCDS CCDS16802 CCDS50731
HPRD
IMGT
MGI ID MGI:1923062
MGI Symbol Tasp1
EMBL AK036512 AK050603 AK146320 AL844881 AL929001 BC005776 BC024597
GenPept AAH05776 AAH24597 BAC29457 BAC34335 BAE27075
RNA Seq Atlas 75812