Version 5.4
| Mus musculus Protein: Rin2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-261186.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rin2 | ||||||||
| Protein Name | Ras and Rab interactor 2 | ||||||||
| Synonyms | 2010003K16Rik; 4632403N06Rik; AW821980; RASSF4; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000105632 | ||||||||
| InnateDB Gene | IDBG-208663 (Rin2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1921280 | ||||||||
| InterPro |
IPR000159
Ras-association IPR000980 SH2 domain IPR003123 Vacuolar sorting protein 9 IPR013995 Vacuolar sorting protein 9, subgroup IPR029071 Ubiquitin-related domain |
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| PFAM |
PF00788
PF00017 PF14633 PF02204 |
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| PRINTS |
PR00401
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| PIRSF | |||||||||
| SMART |
SM00314
SM00252 SM00167 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9D684 | ||||||||
| PhosphoSite | PhosphoSite-Q9D684 | ||||||||
| TrEMBL | Q3TR60 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 74030 | ||||||||
| UniGene | Mm.433263 | ||||||||
| RefSeq | XP_006500332 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Rin2 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK014548 AK040763 AK150680 AK151332 AK152893 AK163047 AK171064 AL672100 BC005529 BC040390 BI660407 | ||||||||
| GenPept | AAH05529 AAH40390 BAB29425 BAC30697 BAE29760 BAE30311 BAE31576 BAE37170 BAE42223 CAM14337 | ||||||||