InnateDB Protein
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IDBP-261249.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Eef1d
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Protein Name
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eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
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Synonyms
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EF-1-delta;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000105602
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InnateDB Gene
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IDBG-151679 (Eef1d)
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Protein Structure
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Function |
Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1- alpha for another round of transfer of aminoacyl-tRNAs to the ribosome. {ECO:0000250}.Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE). {ECO:0000250}.
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Subcellular Localization |
Isoform 2: Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.
Experimentally validated |
Total |
22
[view]
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Protein-Protein |
22
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
80 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1913906
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InterPro |
IPR014038
Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange
IPR018940
Elongation factor 1 beta central acidic region, eukaryote
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PFAM |
PF00736
PF10587
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PRINTS |
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PIRSF |
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SMART |
SM00888
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TIGRFAMs |
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Modification |
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SwissProt |
P57776
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PhosphoSite |
PhosphoSite-P57776
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TrEMBL |
Q9CVV2
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UniProt Splice Variant |
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Entrez Gene |
66656
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UniGene |
Mm.258927
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RefSeq |
XP_006521324
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MGI ID |
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MGI Symbol |
Eef1d
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OMIM |
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CCDS |
CCDS27553
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HPRD |
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IMGT |
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EMBL |
AC116520
AF304351
AK006403
AK010308
AK010347
AK017616
AK017796
AK044934
BC079855
CH466545
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GenPept |
AAG17466
AAH79855
BAB24571
BAB26870
BAB30841
BAC32149
EDL29499
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