Version 5.4
Mus musculus Protein: Dynlrb1
Summary
InnateDB Protein IDBP-261874.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dynlrb1
Protein Name dynein light chain roadblock-type 1
Synonyms 2010012N15Rik; 2010320M17Rik; 9430076K19Rik; AV124457; Dncl2a; DNLC2A; km23-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000105304
InnateDB Gene IDBG-210536 (Dynlrb1)
Protein Structure
UniProt Annotation
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Subcellular Localization Cytoplasm, cytoskeleton.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006810 transport
GO:0007632 visual behavior
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1914318
InterPro IPR004942 Dynein light chain-related
IPR016561 Dynein light chain, roadblock-type
PFAM PF03259
PRINTS
PIRSF PIRSF009998
SMART SM00960
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P62627
PhosphoSite PhosphoSite-P62627
TrEMBL
UniProt Splice Variant
Entrez Gene 67068
UniGene
RefSeq NP_080223
MGI ID 1Y4O
MGI Symbol Dynlrb1
OMIM
CCDS CCDS38294
HPRD
IMGT
EMBL AK002359 AK003435 AK008595 AK166685 AL929588 BC099423 BC125610 BC125648
GenPept AAH99423 AAI25611 AAI25649 BAB22038 BAB22788 BAB25768 BAE38944 CAM27181

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca