InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BICD1

Summary

InnateDB Protein

IDBP-26227.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BICD1

Protein Name

bicaudal D homolog 1 (Drosophila)

Synonyms

BICD;

Species

Homo sapiens

Ensembl Protein

ENSP00000281474

InnateDB Gene

IDBG-26225 (BICD1)

Protein Structure

UniProt Annotation

Function

Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.

Subcellular Localization

Golgi apparatus.

Disease Associations

Tissue Specificity

Expressed in the brain, heart and skeletal muscle.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0008093	cytoskeletal adaptor activity
GO:0017137	Rab GTPase binding
GO:0031871	proteinase activated receptor binding
GO:0034452	dynactin binding
GO:0045502	dynein binding

Biological Process

GO:0006396	RNA processing
GO:0006810	transport
GO:0008298	intracellular mRNA localization
GO:0009653	anatomical structure morphogenesis
GO:0016032	viral process
GO:0033365	protein localization to organelle
GO:0034063	stress granule assembly
GO:0048260	positive regulation of receptor-mediated endocytosis
GO:0072385	minus-end-directed organelle transport along microtubule
GO:0072393	microtubule anchoring at microtubule organizing center
GO:1900275	negative regulation of phospholipase C activity
GO:1900276	regulation of proteinase activated receptor activity
GO:1900737	negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway

Cellular Component

GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005881	cytoplasmic microtubule
GO:0016020	membrane
GO:0031410	cytoplasmic vesicle
GO:0045298	tubulin complex
GO:0048471	perinuclear region of cytoplasm
GO:0072517	host cell viral assembly compartment