Version 5.4
Homo sapiens Gene: BICD1
Summary
InnateDB Gene IDBG-26225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BICD1
Gene Name bicaudal D homolog 1 (Drosophila)
Synonyms BICD
Species Homo sapiens
Ensembl Gene ENSG00000151746
Encoded Proteins
IDBP-26227
bicaudal D homolog 1 (Drosophila)
IDBP-238920
bicaudal D homolog 1 (Drosophila)
IDBP-594176
bicaudal D homolog 1 (Drosophila)
IDBP-602563
bicaudal D homolog 1 (Drosophila)
IDBP-583155
bicaudal D homolog 1 (Drosophila)
IDBP-602614
bicaudal D homolog 1 (Drosophila)
IDBP-813532
bicaudal D homolog 1 (Drosophila)
IDBP-813534
bicaudal D homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:32106835-32383633
Strand Forward strand
Band p11.21
Transcripts
ENST00000281474 ENSP00000281474
ENST00000395758 ENSP00000379107
ENST00000551848 ENSP00000448933
ENST00000550207 ENSP00000447663
ENST00000548411 ENSP00000446793
ENST00000551086 ENSP00000447238
ENST00000547680 ENSP00000475837
ENST00000552160 ENSP00000481877
ENST00000552226
ENST00000614004
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0008093 cytoskeletal adaptor activity
GO:0017137 Rab GTPase binding
GO:0031871 proteinase activated receptor binding
GO:0034452 dynactin binding
GO:0043565 sequence-specific DNA binding
GO:0045502 dynein binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006396 RNA processing
GO:0006810 transport
GO:0008298 intracellular mRNA localization
GO:0009653 anatomical structure morphogenesis
GO:0016032 viral process
GO:0033365 protein localization to organelle
GO:0034063 stress granule assembly
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0072385 minus-end-directed organelle transport along microtubule
GO:0072393 microtubule anchoring at microtubule organizing center
GO:1900275 negative regulation of phospholipase C activity
GO:1900276 regulation of proteinase activated receptor activity
GO:1900737 negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005881 cytoplasmic microtubule
GO:0016020 membrane
GO:0031410 cytoplasmic vesicle
GO:0045298 tubulin complex
GO:0048471 perinuclear region of cytoplasm
GO:0072517 host cell viral assembly compartment
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003452
View Gene Order
ENSBTAG00000006734
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.505202 Hs.620553 Hs.633204
RefSeq NM_001003398 NM_001714
HUGO
OMIM
CCDS CCDS44859 CCDS8726
HPRD 03730
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca