Mus musculus Protein: Wnt7b
Summary
InnateDB Protein IDBP-262415.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Wnt7b
Protein Name wingless-related MMTV integration site 7B
Synonyms Wnt-7b;
Species Mus musculus
Ensembl Protein ENSMUSP00000105051
InnateDB Gene IDBG-170604 (Wnt7b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005109 frizzled binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001944 vasculature development
GO:0003338 metanephros morphogenesis
GO:0007165 signal transduction
GO:0007257 activation of JUN kinase activity
GO:0007267 cell-cell signaling
GO:0007275 multicellular organismal development
GO:0008284 positive regulation of cell proliferation
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0016332 establishment or maintenance of polarity of embryonic epithelium
GO:0021871 forebrain regionalization
GO:0022009 central nervous system vasculogenesis
GO:0030182 neuron differentiation
GO:0030324 lung development
GO:0031175 neuron projection development
GO:0032364 oxygen homeostasis
GO:0032536 regulation of cell projection size
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042592 homeostatic process
GO:0044237 cellular metabolic process
GO:0045165 cell fate commitment
GO:0045669 positive regulation of osteoblast differentiation
GO:0045879 negative regulation of smoothened signaling pathway
GO:0046330 positive regulation of JNK cascade
GO:0048144 fibroblast proliferation
GO:0048568 embryonic organ development
GO:0048812 neuron projection morphogenesis
GO:0050808 synapse organization
GO:0051145 smooth muscle cell differentiation
GO:0051384 response to glucocorticoid
GO:0060033 anatomical structure regression
GO:0060070 canonical Wnt signaling pathway
GO:0060425 lung morphogenesis
GO:0060428 lung epithelium development
GO:0060482 lobar bronchus development
GO:0060484 lung-associated mesenchyme development
GO:0060535 trachea cartilage morphogenesis
GO:0060560 developmental growth involved in morphogenesis
GO:0060669 embryonic placenta morphogenesis
GO:0060710 chorio-allantoic fusion
GO:0061180 mammary gland epithelium development
GO:0071300 cellular response to retinoic acid
GO:0072053 renal inner medulla development
GO:0072054 renal outer medulla development
GO:0072060 outer medullary collecting duct development
GO:0072061 inner medullary collecting duct development
GO:0072089 stem cell proliferation
GO:0072205 metanephric collecting duct development
GO:0072207 metanephric epithelium development
GO:0072236 metanephric loop of Henle development
GO:1902262 apoptotic process involved in patterning of blood vessels
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:98962
InterPro IPR005817 Wnt
IPR013300 Wnt-7 protein
PFAM PF00110
PRINTS PR01349
PR01891
PIRSF
SMART SM00097
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q6NZR1
TrEMBL Q6NZR1
UniProt Splice Variant
Entrez Gene 22422
UniGene Mm.412873
RefSeq NP_001157106
MGI ID
MGI Symbol Wnt7b
OMIM
CCDS CCDS49692
HPRD
IMGT
EMBL AC115763 BC066003
GenPept AAH66003