Version 5.4
Mus musculus Protein: Gabrg2
Summary
InnateDB Protein IDBP-262704.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Gabrg2
Protein Name gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
Synonyms GABAA-R; Gabrg-2; gamma2;
Species Mus musculus
Ensembl Protein ENSMUSP00000104913
InnateDB Gene IDBG-163458 (Gabrg2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004890 GABA-A receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006821 chloride transport
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0007268 synaptic transmission
GO:0009791 post-embryonic development
GO:0030534 adult behavior
GO:0034220 ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030424 axon
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:95623
InterPro IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit
IPR005437 Gamma-aminobutyric-acid A receptor, gamma subunit
IPR005439 Gamma-aminobutyric-acid A receptor, gamma 2 subunit
IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
PFAM PF02932
PF02931
PRINTS PR01079
PR01620
PR01622
PR00253
PR00252
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C7N0
UniProt Splice Variant
Entrez Gene 14406
UniGene Mm.5309
RefSeq
MGI ID
MGI Symbol Gabrg2
OMIM
CCDS
HPRD
IMGT
EMBL AK049857 AL645751 BX284629
GenPept BAC33961

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca