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InnateDB Protein
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IDBP-262819.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Stau1
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Protein Name
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staufen (RNA binding protein) homolog 1 (Drosophila)
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Synonyms
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5830401L18Rik; AW549911; C85792; Stau;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000104859
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InnateDB Gene
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IDBG-212962 (Stau1)
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Protein Structure
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| Function |
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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| Subcellular Localization |
Cytoplasm {ECO:0000250}. Rough endoplasmic reticulum. Note=Localizes exclusively with the rough reticulum endoplasmic (RER).
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 53 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
6
[view]
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| Protein-Protein |
6
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
53 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1338864
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| InterPro |
IPR014720
Double-stranded RNA-binding domain
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| PFAM |
PF00035
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| PRINTS |
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| PIRSF |
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| SMART |
SM00358
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q9Z108
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| PhosphoSite |
PhosphoSite-Q9Z108
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
20853
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| UniGene |
Mm.73276
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| RefSeq |
NP_035620
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| MGI ID |
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| MGI Symbol |
Stau1
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| OMIM |
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| CCDS |
CCDS17093
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| HPRD |
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| IMGT |
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| EMBL |
AF061942
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| GenPept |
AAD17529
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Version 5.4