Version 5.4
Mus musculus Protein: Mgat1
Summary
InnateDB Protein IDBP-262914.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mgat1
Protein Name mannoside acetylglucosaminyltransferase 1
Synonyms Mgat-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000104817
InnateDB Gene IDBG-166792 (Mgat1)
Protein Structure
UniProt Annotation
Function Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
Subcellular Localization Golgi apparatus membrane; Single-pass type II membrane protein.
Disease Associations
Tissue Specificity Appears to be present in all tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
GO:0008375 acetylglucosaminyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006049 UDP-N-acetylglucosamine catabolic process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:96973
InterPro IPR004139 Glycosyl transferase, family 13
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF03071
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P27808
PhosphoSite PhosphoSite-
TrEMBL Q544F0
UniProt Splice Variant
Entrez Gene 17308
UniGene Mm.196933
RefSeq NP_001103619
MGI ID
MGI Symbol Mgat1
OMIM
CCDS CCDS24602
HPRD
IMGT
EMBL AK004760 AK040121 AK087959 AK155322 AL606829 BC006629 CH466575 L07037 M73491
GenPept AAA37698 AAA40478 AAH06629 BAB23541 BAC30515 BAC40058 BAE33189 EDL33761 EDL33762 EDL33763 EDL33764

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca