InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Usp10

Summary

InnateDB Protein

IDBP-263338.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Usp10

Protein Name

ubiquitin specific peptidase 10

Synonyms

2610014N07Rik; mKIAA0190; UBPO; Uchrp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104610

InnateDB Gene

IDBG-196026 (Usp10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0004197	cysteine-type endopeptidase activity
GO:0004221	ubiquitin thiolesterase activity
GO:0004843	ubiquitin-specific protease activity
GO:0036459	ubiquitinyl hydrolase activity
GO:0044325	ion channel binding

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0010506	regulation of autophagy
GO:0016579	protein deubiquitination
GO:0030330	DNA damage response, signal transduction by p53 class mediator

Cellular Component

GO:0005634	nucleus
GO:0005769	early endosome
GO:0045111	intermediate filament cytoskeleton

Protein Structure and Domains

PDB ID

MGI:894652

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase

PFAM

PF00443

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3X9U6

UniProt Splice Variant

Entrez Gene

22224

UniGene

Mm.409707

RefSeq

MGI ID

MGI Symbol

Usp10

OMIM

CCDS

HPRD

IMGT

EMBL

AC120144 AC161435

GenPept