InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Anxa6

Summary

InnateDB Protein

IDBP-263590.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Anxa6

Protein Name

annexin A6

Synonyms

Anx6; AnxVI; AW107198; Cabm; Camb;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000104511

InnateDB Gene

IDBG-174493 (Anxa6)

Protein Structure

UniProt Annotation

Function

May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.

Subcellular Localization

Cytoplasm {ECO:0000250}. Melanosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0005544	calcium-dependent phospholipid binding
GO:0008289	lipid binding
GO:0015276	ligand-gated ion channel activity
GO:0015485	cholesterol binding
GO:0042803	protein homodimerization activity
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0006816	calcium ion transport
GO:0006937	regulation of muscle contraction
GO:0034220	ion transmembrane transport
GO:0051260	protein homooligomerization

Cellular Component

GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0031902	late endosome membrane
GO:0042470	melanosome
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome