Version 5.4
Mus musculus Protein: Atox1
Summary
InnateDB Protein IDBP-263652.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atox1
Protein Name ATX1 (antioxidant protein 1) homolog 1 (yeast)
Synonyms AI256639; Atx1;
Species Mus musculus
Ensembl Protein ENSMUSP00000104485
InnateDB Gene IDBG-175293 (Atox1)
Protein Structure
UniProt Annotation
Function Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005375 copper ion transmembrane transporter activity
GO:0005507 copper ion binding
GO:0016531 copper chaperone activity
GO:0032767 copper-dependent protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006825 copper ion transport
GO:0006878 cellular copper ion homeostasis
GO:0006979 response to oxidative stress
GO:0015680 intracellular copper ion transport
GO:0030001 metal ion transport
GO:0035434 copper ion transmembrane transport
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1333855
InterPro IPR006121 Heavy metal-associated domain, HMA
PFAM PF00403
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O08997
PhosphoSite PhosphoSite-O08997
TrEMBL
UniProt Splice Variant
Entrez Gene 11927
UniGene
RefSeq NP_033850
MGI ID
MGI Symbol Atox1
OMIM
CCDS CCDS36158
HPRD
IMGT
EMBL AF004591 AK002432 AL596207 BC027632
GenPept AAB61465 AAH27632 BAB22098 CAI35353

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca