Version 5.4
Mus musculus Protein: Alox12
Summary
InnateDB Protein IDBP-264244.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Alox12
Protein Name arachidonate 12-lipoxygenase
Synonyms 9930022G08Rik; Alox12p; P-12LO;
Species Mus musculus
Ensembl Protein ENSMUSP00000104214
InnateDB Gene IDBG-194005 (Alox12)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID MGI:87998
InterPro IPR001024 PLAT/LH2 domain
IPR001885 Lipoxygenase, mammalian
IPR008976 Lipase/lipooxygenase, PLAT/LH2
IPR013819 Lipoxygenase, C-terminal
PFAM PF01477
PF00305
PRINTS PR00467
PR00087
PIRSF
SMART SM00308
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C587
UniProt Splice Variant
Entrez Gene 11684
UniGene Mm.12286
RefSeq
MGI ID
MGI Symbol Alox12
OMIM
CCDS
HPRD
IMGT
EMBL AK079232 AL669869
GenPept BAC37583

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca